A comparison of the product characteristics of Instillagel® and Endosgel®

A comparison of the product characteristics of Instillagel® and Endosgel® The use of lubricants in urology diagnostic testing and therapy has been a standard procedure for a long time. The decision to use a suitable lubricant gel not only makes the investigations and surgical procedures easier but contributes considerably to their lasting success. With the development of urology as a specialist field and the ever more complex possibilities for investigation and treatment there is also an increase in the requirements for lubricant functions and properties. The preparations Instillagel® and Endosgel® were developed specifically for transurethral surgery and investigations. They are manufactured according to the highest quality standards and perform all the functions required of this particular, highly sensitive field of application:

  • Making investigations and surgical procedures easierInstillagel® and Endosgel® are lubricants on a hydroxyethylcellulose gel base. They have very good lubricant properties and adhere especially well to the mucosa. Through the addition of propylene glycol, which prevents rapid drying and drying out of the gel, Instillagel® also has particularly long-lasting lubricant properties.
  • Protection against injuries by preparing the urethraApplication of Instillagel® and Endosgel® in the form of a ready-to-use syringe permits direct instillation into the urethra. By coating the urethra evenly and completely with the lubricant gel the urethra otherwise collapsed to a star-shaped form is gently dilated and kept open for the procedure about to be performed. The lubricant cylinder produced reduces the friction between urethra and instrument considerably. Injury to the sensitive mucous membrane and subsequent urethral stricture and via falsa is avoided as far as possible.
  • Safety in procedures that use electric currentInstillagel® and Endosgel® have been used successfully in many years of practice for all currently employed electroresection and coagulation procedures and for bipolar electroresection.
  • Reducing the risk of infection......by being sterileInstillagel® and Endosgel® are sterile lubricant gels packed under sterile conditions. The sterility of substance and packaging means that they can be used for surgical procedures and they offer the best possible protection against introduction of bacteria.
  • ...and having an antiseptic effectInstillagel® and Endosgel® have a rapid, comprehensive, experimentally and clinically proven antiseptic effect, based on an active substance combination of chlorhexidine digluconate, methyl- and propyl-4-hydroxybenzoate. Additional eradication of any bacteria present considerably reduces the risk of infection.
  • Pain relief through the anaesthetising effectInstillagel® contains as active ingredient lignocaine hydrochloride which anaesthetises the mucosa. The onset of its broad effect is only 5 minutes after instillation of the gel. The patient experiences no pain in investigations and surgical procedures and is thus more relaxed. Possible iatrogenic injuries that could occur, e.g. if the patient tenses up or jerks are avoided.

When do I choose which lubricant gel? Instillagel® and Endosgel® are both suitable for virtually all indications in the specialist field of urology. If both products are available the circumstances can be a real help in making the decision. The following illustrates which factors can play a decisive role in the choice of preparation:

Cystoscopy with sterile and disinfecting lubricant gels How do I use Instillagel and Endosgel correctly? In the field of urology cystoscopy is a routine investigation that is frequently carried out but which must always be performed carefully and under sterile conditions. As with any transurethral surgery cystoscopy also involves the risk of bacteria being introduced into the urinary tract. Resulting inflammatory complications can be serious especially if residual urine is formed in the bladder. To prevent this occurence the use of a sterile and disinfecting lubricant gel such as Instillagel® or Endosgel® is recommended. Preparation After appropriate preparation of the patient and disinfection of the genitals the lubricant gel is instilled. A little pressure is exerted on the syringe plunger before removing the seal cap to release the piston (the resistance giving way is clearly felt), the rubber cap can then be carefully removed. At first a few drops of the lubricant gel are dripped on to the orifice. The rounded cone of the syringe can then be inserted more easily and securely. Application Instillagel® and Endosgel are supplied in the form of a piston syringe which offers optimal, simple handling: the gel can be instilled into the urethra slowly, evenly and without using pressure.

Dosage In women 6 ml gel is enough to coat the urethra evenly and completely. The average urethral volume for men is 11 ml. As there is no resuction effect during instillation using the piston syringe no tiny bubbles are able to form, thus enabling the glass-clear gel to provide a perfect view for the imminent investigation. CAUTION! When using Instillagel® the investigation should only be started 5-10 minutes after instillation of the gel to allow the anaesthetising effect to develop fully. In male patients the use of a penis clamp is recommended to prevent the gel flowing out during the waiting period.

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